Probiotics and Microbiota-Host Interaction
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The Probiotics and Microbiota–Host Interactions Group (PMHI) is recognized for its pioneering work in Serbia in the fields of probiotics, host–microorganism interactions, and gut microbiota. Our team includes molecular microbiologists, molecular geneticists, immunologists, pharmacists, biochemists, and bioinformaticians. Our research is dedicated to studying the interactions between beneficial bacteria and their hosts (humans and animals), as well as understanding the molecular mechanisms underlying these interactions.
The PMHI Group’s research topics include:
- Microbiota–Gut–Brain Axis – Investigating the connection between gut microbiota and neuropsychiatric disorders.
- Microbiota and Systemic Diseases – Studying the role of microbiota in immunotherapy, autoimmune diseases, diabetes, and aging.
- Probiotics and Postbiotics – Characterizing natural isolates of lactic acid bacteria and anaerobic gut bacteria, identifying bioactive bacterial metabolites, and developing next-generation probiotics.
- Functional Food and Gut Health – Analyzing and isolating microorganisms and bioactive components from fermented products (bread, dairy products), testing starter cultures with probiotic effects for the preparation of these products, and studying their impact on gut physiology.
The group’s goal is to develop effective, scientifically based therapies focused on microbiota modulation, as well as probiotics and functional products that strengthen the host’s defense mechanisms and improve the health and quality of life of both humans and animals. The group has established and continues to develop the first national collection of indigenous microorganisms – LABBANK. Our innovative activities are implemented through the Center for Probiotics and Starter Cultures.
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Nataša Golić
Full Research ProfessorGroup for Probiotics and Microbiota-Host Interaction
Department of Microbiology and Plant BiologyNataša Golić is a Full Research Professor and Head of the Probiotics and Microbiota-Host Interaction Group. She has been employed by IMGGE since 1994.
Since 2024, she has been the Head of the Department of Microbiology and Plant Biology.
The main research interest of Nataša Golić is related to the role of gut microbiota and probiotics in various autoimmune diseases, aging and the gut-brain axis. In particular, she is interested in the development of novel therapeutics and the application of probiotics for the prevention and treatment of various non-communicable diseases and conditions (type 2 diabetes, multiple sclerosis, autism, inflammatory pain, depression, aging). Her recent work is related to the characterization of novel extremely oxygen-sensitive gut bacteria as potential next-generation probiotics (PI of NextGenBiotics project funded by Science Fund, Republic of Serbia). She is a mentor of a number of master's and doctoral theses and the author of 93 research papers published in peer-reviewed international journals, five book chapters and one national and international patent (PCT).
Nataša Golić is active in technology transfer, as the first Head of Technology Transfer Sector at IMGGI since 2016 to 2023. She is a mentor and motivational trainer to encourage researchers to commercialize their knowledge and innovations and start their own business. Nataša Golić is cofounder of two spinout companies of IMGGE: Invetlab, founded with the aim of development and commercialization of innovative probiotics for humans and animals and DIASOLUTION, founded with the aim of commercialization of innovative probiotic for diabetes management, the first probiotic developed in IMGGE that passed clinical trial at the University Clinical Centre in Belgrade, Serbia, at the Department of Endocrinology, Diabetes and Metabolic Diseases.
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FULL RESEARCH PROFESSOR
ASSOCIATE RESEARCH PROFESSOR
ASSISTANT RESEARCH PROFESSOR
RESEARCH ASSISTANT