Marija Mojsin

Associate Research Professor
Laboratory for human molecular genetics

Institute of molecular genetics and genetic engineering (IMGGE),
University of Belgrade

Vojvode Stepe 444a, 11042 Belgrade 152, Serbia
Mobile:  +381 65 3976 212                          
Phone:   +381 11  3976 212
Fax:       +381 11 397 58 08


2008 - PhD in Biology, Faculty of Biology (FB), UB (The role of TALE transcription factors in the retinoic acid induced activation of SOX3 gene)
2000 - M.Sc. in Biology, FB, UB
1997 - B.Sc. in Molecular biology and physiology, FB, University of Belgrade


2017 - Senior Research Associate, IMGGE, UB
2009 -  Research Associate,IMGGE
2000 - 2009 - Research Assistant, IMGGE
1997 - 2000 - Research Trainee, IMGGE


2019 - Vice President of the Scientific Council, Institute of molecular genetics and genetic engineering (IMGGE), University of Belgrade (UB)
2017 - 2019 President of the Scientific Council, IMGGE, UB
2016 - Member of the Steering Committee of the Serbian Society forMolecular Biology
2013 - Lecturer on Faculty of Biology, University of Belgrade on Doctoralstudy program Molecular biology of eukaryotes
2011 - Deputy Head of Laboratory for human molecular genetics, IMGGE


Mechanisms involved in the regulation of human SOX3 gene expression during neural differentiation: transcription factors, signalling pathways, epigenetic modifications

The role of Wnt/β-catenin signaling pathway in the regulation of human SOXB1 genes (SOX1, SOX2 and SOX3) expression

In vitro examination of bioactive compounds (effects on cell viability, proliferation, apoptosis, cel adhesion, migration capacity and redox status) in order to evaluate their potential for improving human nutrition and health.


Benzothiazole carbamates and amides as antiproliferative species. Videnović M, Mojsin M, Stevanović M, Opsenica I, Srdić-Rajić T, Šolaja B. Eur J Med Chem. 2018 Sep 5;157:1096-1114. doi: 10.1016/j.ejmech.2018.08.067.

Does Dietary Provision of Guanidinoacetic Acid Induce Global DNA Hypomethylation in Healthy Men and Women? Ostojic SM, Mojsin M, Drid P, Vranes M. Lifestyle Genom. 2018;11(1):16-18. doi: 10.1159/000487336.

Epigenetic regulation of human SOX3 gene expression during early phases of neural differentiation of NT2/D1 cells. Topalovic V, Krstic A, Schwirtlich M, Dolfini D, Mantovani R, Stevanovic M, Mojsin M. PLoS One. 2017 Sep 8;12(9):e0184099. doi: 10.1371/journal.pone.0184099. eCollection 2017.

Histone Modifications on the Promoters of Human OCT4 and NANOG Genes at the Onset of Neural Differentiation of NT2/D1 Cells.Topalovic V, Schwirtlich M, Stevanovic M, Mojsin M. Biochemistry (Mosc). 2017 Jun;82(6):715-722. doi: 10.1134/S0006297917060086.

Crosstalk between SOXB1 proteins and WNT/β-catenin signaling in NT2/D1 cells Mojsin M, Topalovic V, Vicentic JM, Schwirtlich M, Stanisavljevic D, Drakulic D, Stevanovic M. Histochem Cell Biol. 2015 Nov;144(5):429-41. doi: 10.1007/s00418-015-1352-0. Epub 2015 Aug 4.

Human embryonal carcinoma cells in serum-free conditions as an in vitro model system of neural differentiation. Jasnic-Savovic J, Klajn A, Milivojevic M, Mojsin M, Nikcevic G. Altern Lab Anim. 2015 Mar;43(1):9-18.

Transcription factor NF-Y inhibits cell growth and decreases SOX2 expression in human embryonal carcinoma cell line NT2/D1. Mojsin M, Topalovic V, Marjanovic Vicentic J, Stevanovic M. Biochemistry (Mosc). 2015 Feb;80(2):202-7. doi: 10.1134/S0006297915020066.

Antioxidant and antiproliferative activity of chokeberry juice phenolics during in vitro simulated digestion in the presence of food matrix. Stanisavljević N, Samardžić J, Janković T, Šavikin K, Mojsin M, Topalović V, Stevanović M. Food Chem. 2015 May 15;175:516-22. doi: 10.1016/j.foodchem.2014.12.009. Epub 2014 Dec 10.

Quercetin reduces pluripotency, migration and adhesion of human teratocarcinoma cell line NT2/D1 by inhibiting Wnt/β-catenin signaling. Mojsin M, Vicentic JM, Schwirtlich M, Topalovic V, Stevanovic M. Food Funct. 2014 Oct 24;5(10):2564-73. doi: 10.1039/c4fo00484a. Epub 2014 Aug 20.

Construction and functional analysis of novel dominant-negative mutant of human SOX18 protein. Milivojevic M, Petrovic I, Kovacevic-Grujicic N, Popovic J,Mojsin M, Stevanovic M. Biochemistry (Mosc). 2013 Nov;78(11):1287-92. doi: 10.1134/S0006297913110096.

Cyclic AMP response element binding (CREB) protein acts as a positive regulator of SOX3 gene expression in NT2/D1 cells. Kovacevic-Grujicic N,Mojsin M, Popovic J, Petrovic I, Topalovic V, Stevanovic M. BMB Rep. 2014 Apr;47(4):197-202.

TG-interacting factor (TGIF) downregulates SOX3 gene expression in the NT2/D1 cell line. Mojsin M, Popovic J, Kovacevic Grujicic N, Stevanovic M. J Genet Genomics. 2012 Jan;39(1):19-27. doi: 10.1016/j.jgg.2011.11.006. Epub 2011 Dec 24.

Regulation of the SOX3 gene expression by retinoid receptors. Nikčević G, Kovačević-Grujičić N,Mojsin M, Krstić A, Savić T, Stevanović M. Physiol Res. 2011;60 Suppl 1:S83-91. Epub 2011 Jul 19. Review.

Comparative analysis of SOX3 protein orthologs: Expansion of homopolymeric amino acid tracts during vertebrate evolution. Mojsin M, Kovacevic-Grujicic N, Krstic A, Popovic J, Milivojevic M, Stevanovic M. Biochem Genet. 2010 Aug;48(7-8):612-23. doi: 10.1007/s10528-010-9343-2. Epub 2010 May 21.

PBX1 and MEIS1 up-regulate SOX3 gene expression by direct interaction with a consensus binding site within the basal promoter region. Mojsin M, Stevanovic M. Biochem J. 2009 Dec 14;425(1):107-16. doi: 10.1042/BJ20090694.

Regulation of SOX3 gene expression is driven by multiple NF-Y binding elements. Krstic A,Mojsin M, Stevanovic M. Arch Biochem Biophys. 2007 Nov  5;467(2):163-73.

Comparison of promoter regions of SOX3, SOX14 and SOX18 orthologs in mammals. Kovacevic-Grujicic N,Mojsin M, Djurovic J, Petrovic I, Stevanovic M. DNA Seq. 2008 Jun;19(3):185-94.

Mapping of the RXRalpha binding elements involved in retinoic acid induced transcriptional activation of the human SOX3 gene. Mojsin M, Grujicić NK, Nikcević G, Krstić A, Savić T, Stevanović M. Neurosci Res. 2006 Dec;56(4):409-18.

Functional characterization of the human SOX3 promoter: identification of transcription factors implicated in basal promoter activity. Kovacevic Grujicic N,Mojsin M, Krstic A, Stevanovic M. Gene. 2005 Jan 3;344:287-97

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