Jovana Komazec

Assistant Research Professor
Laboratory for Molecular Biomedicine

Institute of molecular genetics and genetic engineering (IMGGE),
University of Belgrade

Vojvode Stepe 444a, 11042 Belgrade 152, Serbia
Mobile: +381 65 397 64 45
Phone: +381 11 397 64 45
Fax: +381 11 397 58 08
E-mail: jovana.vasiljevic@imgge.bg.ac.rs

EDUCATION

2020. - PhD in Molecular Biology, Faculty of Biology (FB), University of Belgrade (UB)
(Thesis: Coding and noncoding variants of disease-causing genes of maturity-onset diabetes of the young: phenotype modulators and regulators of gene expression)
2012. - Diploma (equivalent to M.Sc.) in Molecular biology and physiology, FB, UB

RESEARCH EXPERIENCE

2020. - Assistant Research Professor at Laboratory for Molecular Biomedicine, IMGGE
2016. 2020. - Research Assistant, Laboratory for Molecular Biomedicine, IMGGE
2015. – 2016. - Research Trainee, Laboratory for Molecular Biomedicine, IMGGE
2012. – 2013. - Volunteer at the Institute of Medical Research, Military Medical Academy, Belgrade.

CAREER HISTORY

2015.  – present – Researcher at Laboratory for Molecular Biomedicine, IMGGE.
2013. – 2014. - Teaching assistant on the course Biology and Human genetics, Faculty of Pharmacy, Department of Physiology; University of Belgrade.

RESEARCH INTEREST

The scientific research area - genetic basis of MODY diabetes (Maturity-onset diabetes of the Young, MODY), functional characterization of disease-causing gene variants and genotype - phenotype correlation.

MODY diabetes is a rare, monogenic form of diabetes with autosomal-dominant inheritance. To date, more than thirteen genes causing MODY diabetes have been identified. Genetic diagnosis is crucial as the therapy depends on the MODY-related gene and prognosis of the disease.

SELECTED PUBLICATIONS

  1. Komazec J, Zdravkovic V, Sajic S, Jesic M, Andjelkovic M, Pavlovic S, Ugrin M. The importance of combined NGS and MLPA genetic tests for differential diagnosis of Maturity onset diabetes of the young. Endokrinol Pol. 2019; 70(1):28-36. https://pubmed.ncbi.nlm.nih.gov/30259503/
  2. Komazec J, Ristivojevic B, Zukic B, Zdravkovic V, Karan-Djurasevic T, Pavlovic S, Ugrin M. Analysis of the promoter regions of disease-causing genes in maturity-onset diabetes of the young patients. Mol Biol Rep. 2020 Sep;47(9):6759-6768. https://pubmed.ncbi.nlm.nih.gov/32860162/
  3. Ugrin M, Milacic I, Skakic A, Klaassen K, Komazec J, Pavlovic S, Stojiljkovic M. Molecular genetic strategy for diagnosis of congenital adrenal hyperplasia in Serbia. Genetika. 2017; 49(2):457-467. http://www.doiserbia.nb.rs/Article.aspx?id=0534-00121702457U#.YEiW7ehKhPY
  4. Andjelkovic M, Spasovski V, Vreca M, Sovtic A, Rodic M, Komazec J, Pavlovic S, Minic P. The importance of genomic profiling for differential diagnosis of pediatric lung disease patients with suspected ciliopathies. Srpski arhiv za celokupno lekarstvo. 2019; 147(3-4):160-166. http://www.doiserbia.nb.rs/Article.aspx?id=0370-81791900012A#.YEiXT-hKhPY
  5. Stjepanovic M, Mihailovic-Vucinic V, Spasovski V, Milin-Lazovic J, Skodric-Trifunovic V, Stankovic S, Andjelkovic M, Komazec J, Momcilov A, Santric-Milicevic M, Pavlovic S. Genes and metabolic pathway of sarcoidosis: identification of key players and risk modifiers. Arch Med Sci. 2019. (5):1138-1146. https://pubmed.ncbi.nlm.nih.gov/31572458/
  6. Ugrin M, Stojiljkovic M, Zukic B, Klaassen K, Katsila T, Vasiljevic J, Dokmanovic L, Janic D, Patrinos GP, Pavlovic S. Functional Analysis of an Aγ-Globin Gene Promoter Variant (HBG1: g.-225_-222delAGCA) Underlines Its Role in Increasing Fetal Hemoglobin Levels Under Erythropoietic Stress. Hemoglobin. 2016; 40(1):48-52. https://pubmed.ncbi.nlm.nih.gov/26575252/

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