Lidija Šenerović

Viši naučni saradnik
Laboratorija za molekularnu genetiku i ekologiju mikroorganizama (LMGEM)

Institut za molekularnu genetiku i genetičko inženjerstvo (IMGGI),
Univerzitet u Beogradu (UB)

Vojvode Stepe 444a, 11042 Beograd 152, Srbija
Mob:   +381 65 397 60 34  
Tel:     +381 11 397 60 34
Fax:    +381 11 397 58 08
E-mail: seneroviclidija@imgge.bg.ac.rs

OBRAZOVANJE

2009 - Doktor bioloških nauka (specijalizacija: biohemija), Humboldt Univerzitet, Berlin, Nemačka
(TEZA: Funkcionalna i strukturna karakterizacija virulentnog faktora IpaB iz Shigella flexneri)
2005 - Magistar bioloških nauka, Biološki fakultet, UB
2001 - Diplomirani molekularni biolog i fiziolog, Biološki fakultet, UB

ISTRAŽIVAČKO ISKUSTVO

2016 - Viši naučni saradnik, Laboratorija za molekularnu genetiku i ekologiju mikroorganizama, IMGGI, UB
2011 - 2016
- Naučni saradnik, Laboratorija za molekularnu genetiku i ekologiju mikroorganizama, IMGGI, UB
2006 - 2009 - Doktorand u Laboratoriji za ćelijsku mikrobiologiju, Max Planck Institut za infektivnu biologiju, Berlin, Nemačka
2005 - 2006 - Istraživač saradnik, Laboratorija za molekularnu biotehnologiju, IMGGI, UB
2002 - 2005 - Istraživač pripravnik, Laboratorija za molekularnu biotehnologiju, IMGGI, UB

OBLAST NAUČNOG INTERESOVANJA

  • Proizvodnja i karakterizacija bioaktivnih jedinjenja sa antibakterijskim i antigljivičnim aktivnostima;
  • Novi pristupi u antimikrobiološkim tretmanima (novi molekuli koji modulišu mikrobiološku komunikaciju; agensi koji modulišu virulenciju i sprečavaju formiranje biofilmova bakterija i gljiva);
  • Domaćin-patogen interakcije;
  • Razvoj novih i efikasnijih terapeutika korišćenjem nano-nosača.

ODABRANI NAUČNI RADOVI

Aleksic, I., Jeremic, J., Milivojevic, D., Ilic-Tomic, T., Šegan, S., Zlatović, M., Opsenica D. and Senerovic, L. (2019). N-benzyl derivatives of long-chained 4-Amino-7-chloro-quionolines as inhibitors of pyocyanin production in Pseudomonas aeruginosa. ACS Chem Biol 14(12):2800-2809https://www.ncbi.nlm.nih.gov/pubmed/31647218

Senerovic, L., Opsenica, D., Moric, I., Aleksic, I., Spasić, M and Vasiljevic, B (2019). Quinolines and quinolones as antibacterial, antifungal, anti-virulence, antiviral and anti-parasitic agents. Advances in Experimental Medicine and Biology. Springer, New York, NY. https://www.ncbi.nlm.nih.gov/pubmed/31515709

Zizovic I., Senerovic L., Moric I., Adamovic T., Jovanovic M., Kalagasidis Krusic M., Misic D., Stojanovic D. and Milovanovic S (2018). Utilization of supercritical carbon dioxide in fabrication of cellulose acetate films with anti-biofilm effects against Pseudomonas aeruginosa and Staphylococcus aureus. Jour Supercritical Fluids. 140:11-20 https://www.sciencedirect.com/science/article/pii/S0896844618300913

Aleksic I., Ristivojevic P., Pavic A., Radojević I., Čomić Lj., Vasiljevic B., Opsenica D., Milojković-Opsenica D. and Senerovic L. (2018).  Anti-quorum sensing activity, toxicity in zebrafish (Danio rerio) embryos and phytochemical characterization of Trapa natans leaf extracts. Jour Ethnopharm 222:148-158https://www.ncbi.nlm.nih.gov/pubmed/29733941

Aleksic I., Petkovic M., Jovanovic M., Milivojevic D., Vasiljevic B., Nikodinovic-Runic J.  and  Senerovic L. (2017). Anti-biofilm properties of bacterial di-rhamnolipids and their semi-synthetic amide derivatives. Front Microbiol 8;8:2454 https://www.frontiersin.org/articles/10.3389/fmicb.2017.02454/full

Aleksić I., Šegan S., Andrić F., Zlatović M., Moric I., Opsenica D. and Senerovic L. (2017). Long-chained 4-Aminoquinolines as quorum sensing inhibitors in Serratia marcescens and Pseudomonas aeruginosa. ACS Chem Biol 12(5):1425-1434 https://www.ncbi.nlm.nih.gov/pubmed/28350449

Pekmezovic M., Aleksic I., Barac A., Arsic-Arsnijevic V., Vasiljevic B., Nikodinovic-Runic J. and Senerovic L. (2016). Prevention of polymicrobial biofilms composed of Pseudomonas aeruginosa and pathogenic fungi by essential oils from selected Citrus species. Pathog Dis (2016) 74 (8): ftw102.https://www.ncbi.nlm.nih.gov/pubmed/27702795

Milisavljevic M., Zivkovic S., Pekmezovic M., Stankovic N., Vojnovic S., Vasiljevic B. and Senerovic L. (2015). Control of human and plant fungal pathogens using pentaene macrolide 32, 33- didehydroroflamycoin (DDHR). J Appl Micro 118(6):1426-34 http://www.ncbi.nlm.nih.gov/pubmed/25810243

Nikodinovic-Runic J., Mojic M., Kang Y., Maksimovic-Ivanic D., Mijatovic S., Vasiljevic B., Stamenkovic V., Senerovic L. (2014). Undecylprodigiosin conjugated monodisperse gold nanoparticles efficiently cause apoptosis in colon cancer cells in vitro. J Mater Chem B 2 (21), 3271 - 3281. http://pubs.rsc.org/en/Content/ArticleLanding/2014/TB/c4tb00300d#!divAbstract

Senerovic L., Tsunoda S., Goosmann C., Brinkmann V., Zychlinsky A., Meissner F. and Kolbe M. (2012): Spontaneous formation of IpaB ion channels in host cell membranes reveals how Shigella induces pyroptosis in macrophages Cell Death Dis. Sep 6;3:e384. http://www.ncbi.nlm.nih.gov/pubmed/22951981

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