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Laboratory for Molecular Biomedicine (LMB) is well recognized for its research achievements and expertise in diagnosis of various rare diseases in Serbia as well as in the Balkan region. The research mission of LMB is oriented towards investigation of molecular basis of health and disease and translational biomedicine, in order toimplement genome-based, personalized medicine in healthcare system. LMB has established successful collaborations with a number of distinguished EU centres and their top class scientists resulting in joint papers and partnerships in significant projects. In addition, LMB has successful collaborations with eminent Serbian and Balkan healthcare institutions. Accumulated know-how has been translated into improvement of medical practice through molecular genetic diagnosis of genetic disorders and malignancies. Some of genetic testing in LMB are exclusively done in Balkan region. LMB team is actively engaged in educational activities within University of Belgrade with special emphasis on conducting multidisciplinary PhD thesis.LMB researchers are also devoted to promotion of molecular genetics, genomics and biomedicine at all levels.
- IMGGE work program for 2020
Ministry of Education, Science and Technological Development of the Republic of Serbia, 451-03-68/2020-14/200042, 2020
Principal Investigator: Dr Jelena Begovic, IMGGE
Participants from IMGGE: all employed researchers - Analysis of the synergistic effect and therapeutic potential of small molecules in patients with recurrent pulmonary infections
Proof of Concept, Innovation Fund of the Republic of Serbia, 5269, 2020-2021
Principal Investigator: Dr Marina Andjelkovic, IMGGE
Participants from IMGGE: Dr Sonja Pavlovic, Dr Anita Skakic, Dr Vesna Spasovski, Dr Kristel Klaassen - LEukaemia GENe Discovery by data sharing, mining and collaboration (LEGEND)
COST akcija CA16223, 2017-2021
Participants from IMGGE: Dr Natasa Tosic, dr Sonja Pavlovic - European Network for Innovative Diagnosis and Treatment of Chronic Neutropenias (EuNet-INNOCHRON)
COST akcija CA18233, 2019-2023
Participants from IMGGE: Dr Sonja Pavlovic, dr Anita Skakic, dr Kristel Klaassen, dr Vladimir Gasic, dr Marina Andjelkovic - ADHEsion GPCR Network: Research and Implementation Set the path for future Exploration (Adher'n Rise)
COST akcija CA18240, 2019-2023
Participants from IMGGE: Dr Biljana Stankovic, dr Nikola Kotur -
Short course of DNAlogy
Center for the Promotion of Science, 2020-2021
Principal Investigator: Dr Branka Zukic, IMGGE
Participants from IMGGE: Dr Sonja Pavlovic, dr Milena Ugrin, dr Vesna Spasovski, dr Biljana Stankovic, dr Nikola Kotur, dr Kristel Klaassen Ljubicic, dr Marina Andjelkovic, dr Anita Skakic, dr Vladimir Gasic, Jovana Komazec, Bojan Ristivojevic
- Pharmacogenomic and Pharmacotranscriptomic Profiling of Childhood Acute Lymphoblastic Leukemia: Paving the Way to Personalized Treatment
Pavlovic S, Kotur N, Stankovic B, Zukic B, Gasic V, Dokmanovic L
Genes (Basel) 2019;10(3):E191 - CRISPR/Cas9 genome editing of SLC37A4 gene elucidates the role of molecular markers of endoplasmic reticulum stress and apoptosis in renal involvement in glycogen storage disease type Ib
Skakic A, Andjelkovic M, Tosic N, Klaassen K, Djordjevic M, Pavlovic S, Stojiljkovic M
Gene 2019;703:17-25 - Genomic profiling supports the diagnosis of primary ciliary dyskinesia and reveals novel candidate genes and genetic variants
Andjelkovic M, Minic P, Vreca M, Stojiljkovic M, Skakic A, Sovtic A, Rodic M, Skodric-Trifunovic V, Maric N, Visekruna J, Spasovski V, Pavlovic S
PLoS One 2018;13(10):e0205422 - Intra-articular injection of autologous adipose-derived mesenchymal stem cells in the treatment of knee osteoarthritis
Spasovski D, Spasovski V, Baščarević Z, Stojiljković M, Vreća M, Anđelković M, Pavlović S
J Gene Med 2018;20(1):e3002 - Expanded national database collection and data coverage in the FINDbase worldwide database for clinically relevant genomic variation allele frequencies
Viennas E, Komianou A, Mizzi C, Stojiljkovic M, Mitropoulou C, Muilu J, Vihinen M, Grypioti P, Papadaki S, Pavlidis C, Zukic B, Katsila T, van der Spek PJ, Pavlovic S, Tzimas G, Patrinos GP
Nucleic Acids Res 2017;45(D1):D846-D853 - Parallel targeted next generation sequencing of childhood and adult acute myeloid leukemia patients reveals uniform genomic profile of the disease
Marjanovic I, Kostic J, Stanic B, Pejanovic N, Lucic B, Karan-Djurasevic T, Janic D, Dokmanovic L, Jankovic S, Vukovic NS, Tomin D, Perisic O, Rakocevic G, Popovic M, Pavlovic S, Tosic N
Tumour Biol 2016;37(10):13391-13401 - A European Spectrum of Pharmacogenomic Biomarkers: Implications for Clinical Pharmacogenomics
Mizzi C, Dalabira E, Kumuthini J, Dzimiri N, Balogh I, Başak N, Böhm R, Borg J, Borgiani P, Bozina N, Bruckmueller H, Burzynska B, Carracedo A, Cascorbi I, Deltas C, Dolzan V, Fenech A, Grech G, Kasiulevicius V, Kádaši Ľ, Kučinskas V, Khusnutdinova E, Loukas YL, Macek M Jr, Makukh H, Mathijssen R, Mitropoulos K, Mitropoulou C, Novelli G, Papantoni I, Pavlovic S, Saglio G, Setric J, Stojiljkovic M, Stubbs AP, Squassina A, Torres M, Turnovec M, van Schaik RH, Voskarides K, Wakil SM, Werk A, Del Zompo M, Zukic B, Katsila T, Lee MT, Motsinger-Rief A, Mc Leod HL, van der Spek PJ, Patrinos GP
PLoS One 2016;11(9):e0162866 - Gene Mutation Profiles in Primary Diffuse Large B Cell Lymphoma of Central Nervous System: Next Generation Sequencing Analyses
Todorovic Balint M, Jelicic J, Mihaljevic B, Kostic J, Stanic B, Balint B, Pejanovic N, Lucic B, Tosic N, Marjanovic I, Stojiljkovic M, Karan-Djurasevic T, Perisic O, Rakocevic G, Popovic M, Raicevic S, Bila J, Antic D, Andjelic B, Pavlovic S
Int J Mol Sci 2016;17(5):E683 - Maritime route of colonization of Europe
Paschou P, Drineas P, Yannaki E, Razou A, Kanaki K, Tsetsos F, Padmanabhuni SS, Michalodimitrakis M, Renda MC, Pavlovic S, Anagnostopoulos A, Stamatoyannopoulos JA, Kidd KK, Stamatoyannopoulos G.
Proc Natl Acad Sci U S A 2014;111(25):9211-9216 - Systematic documentation and analysis of human genetic variation in hemoglobinopathies using the microattribution approach
Giardine B, Borg J, Higgs D, Peterson K, Philipsen S, Maglott D, Singleton B, Anstee D, Basak AN, Clark B, Costa F, Faustino P, Fedosyuk H, Felice A, Francina A, Galanello R, Gallivan M, Georgitsi M, Gibbons R, Giordano P, Harteveld C, Hoyer J, Jarvis M, Joly P, Kanavakis E, Kollia P, Menzel S, Miller W, Moradkhani K, Old J, Papachatzopoulou A, Papadakis M, Papadopoulos P, Pavlovic S, Perseu L, Radmilovic M, Riemer C, Satta S, Schrijver I, Stojiljkovic M, Thein SL, Traeger-Synodinos J, Tully R, Wada T, Waye J, Wiemann C, Zukic B, Chui D, Wajcman H, Hardison R, Patrinos P
Nat Genet. 2011;43(4):295-301
Head Office / Mailing address:
Vojvode Stepe 444a,
11042 Belgrade 152, Serbia
Tel: +381 11 3976445
Faks: +381 11 3975808