Đorđe Francuski
Assistant Research Professor
Laboratory for Molecular Biology(LMB)
Institute of molecular genetics and genetic engineering (IMGGE),
University of Belgrade
Vojvode Stepe 444a, 11042 Belgrade 152, Serbia
Mobile: +381 64 4977 603
Phone: +381 11 397 66 58
Fax: +381 11 397 58 08
E-mail: djordjef@imgge.bg.ac.rs
EDUCATION
2009 - PhD in Structural Biology, Freie Universität Berlin, thesis: “The Crystal Structure of Mj RelBE Protein Complex from Methanococcus jannaschii”
2000 - Diploma in Physical Chemistry, Faculty of Physical Chemistry, Belgrade University, graduate thesis work: “Synthesis and characterization of Q-PbS and Polystyrene composites”
RESEARCH EXPERIENCE
2009 - Research Associate,LMB, IMGGE, Belgrade, Serbia
2010 - 2011 - Guest scientist at Freie Universität Berlin, Germany. Institute for Chemistry/Biochemistry and Crystallography (professor Saenger group) and Institute for Biochemistry (professor Erdmann group)
2005 - 2008 - AG Saenger , Institut für Chemie und Biochemie, FU Berlin
2007 - AG Saenger , Institut für Chemie und Biochemie, FU Berlin and AG Kroczek, Molecular Immunology, Robert Koch-Institute. Berlin, Germany
2001 – 2003 - AG Saenger , Institut für Chemie und Biochemie, FU Berlin. Berlin, Germany
RESEARCH INTEREST
Structural and functional relationships of proteins, modeling of protein interactions, studies on mutation influenced changes in structure and function of proteins. X-Ray structure determination of proteins and high resolution structures of small molecules. Theoretical charge density studies on thioureido-based compounds. Oxidative stress markers and their measurement.
SELECTED PUBLICATIONS
Djordjevic, V., Kovac, M., Miljic, P., Murata, M., Takagi, A., Pruner, I., Francuski, D., Kojima, T., Radojkovic, D. A novel prothrombin mutation in two families with prominent thrombophilia - the first cases of antithrombin resistance in a Caucasian population (2013) Journal of Thrombosis and Haemostasis, 11 (10), pp. 1936-1939. http://www.ncbi.nlm.nih.gov/pubmed/23927452
Topic A, Francuski D, Markovic B, Stankovic M, Dobrivojevic S, Drca S, Radojkovic D. (2013) Gender-related reference intervals of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine determined by liquid chromatography-tandem mass spectrometry in Serbian population. Clin Biochem., 46(4-5):321-6. http://www.ncbi.nlm.nih.gov/pubmed/23261837
Narancic, T., Radivojevic, J., Jovanovic, P., Francuski, D., Bigovic, M., Maslak, V., Savic, V., Vasiljevic, B., O'Connor, K.E., Nikodinovic-Runic, J. (2013) Highly efficient Michael-type addition of acetaldehyde to β-nitrostyrenes by whole resting cells of Escherichia coli expressing 4-oxalocrotonate tautomerase Bioresource Technology, 142, pp. 462-46. http://www.ncbi.nlm.nih.gov/pubmed/23759430
Nikodinovic-Runic, J., Coulombel, L., Francuski, D., Sharma, N.D., Boyd, D.R., Ferrall, R.M.O., O'Connor, K.E. (2013) The oxidation of alkylaryl sulfides and benzo[b]thiophenes by Escherichia coli cells expressing wild-type and engineered styrene monooxygenase from Pseudomonas putida CA-3, Applied Microbiology and Biotechnology, 97 (11), pp. 4849-4858. http://www.ncbi.nlm.nih.gov/pubmed/22890778
Francuski B, Ivkovic B, Stojanovic I, Vladimirov S, Francuski D. 2-[2-(Trifluoromethyl)phenyl]-2H-1-benzopyran-4(3H)-one. Acta Crystallogr E. 2012; E68: 01522.
Jacimovic Z, Leovac V, Francuski D, Draskovic B, Bogdanovic G (2009) Crystal structure of dicholoro-(3,5-dimethyl-1H-pyrazole-1-carboxamidine-N,N')copper(II),Cu(C6H10N4)Cl2 Z Kristallogr NCS 224: 569-570.
Francuski D, Saenger W (2009) Crystal Structure of the Antitoxin–Toxin Protein Complex RelB–RelE from Methanococcus jannaschii J Mol Biol 393: 898-908. http://www.ncbi.nlm.nih.gov/pubmed/19712680
Alonso, J. C., Balsa, D., Cherny, I., Christensen, S. K., Espinosa, M., Francuski, D., et al. (2007). Bacterial Toxin-Antitoxin Systems as Targets for the Development of Novel Antibiotics. In R. A. Bonomo, & M. E. Tolmasky (Eds.), Enzyme-Mediated Resistance to Antibiotics: Mechanism, Dissemination, and Prospects for Inhibition (pp. 313-329). Washington, D.C.: ASM Press.
Assistant Research Professor
Laboratory for Molecular Biology(LMB)
Institute of molecular genetics and genetic engineering (IMGGE),
University of Belgrade
Vojvode Stepe 444a, 11042 Belgrade 152, Serbia
Mobile: +381 64 4977 603
Phone: +381 11 397 66 58
Fax: +381 11 397 58 08
E-mail: djordjef@imgge.bg.ac.rs
EDUCATION
2009 - PhD in Structural Biology, Freie Universität Berlin, thesis: “The Crystal Structure of Mj RelBE Protein Complex from Methanococcus jannaschii”
2000 - Diploma in Physical Chemistry, Faculty of Physical Chemistry, Belgrade University, graduate thesis work: “Synthesis and characterization of Q-PbS and Polystyrene composites”
RESEARCH EXPERIENCE
2009 - Research Associate,LMB, IMGGE, Belgrade, Serbia
2010 - 2011 - Guest scientist at Freie Universität Berlin, Germany. Institute for Chemistry/Biochemistry and Crystallography (professor Saenger group) and Institute for Biochemistry (professor Erdmann group)
2005 - 2008 - AG Saenger , Institut für Chemie und Biochemie, FU Berlin
2007 - AG Saenger , Institut für Chemie und Biochemie, FU Berlin and AG Kroczek, Molecular Immunology, Robert Koch-Institute. Berlin, Germany
2001 – 2003 - AG Saenger , Institut für Chemie und Biochemie, FU Berlin. Berlin, Germany
RESEARCH INTEREST
Structural and functional relationships of proteins, modeling of protein interactions, studies on mutation influenced changes in structure and function of proteins. X-Ray structure determination of proteins and high resolution structures of small molecules. Theoretical charge density studies on thioureido-based compounds. Oxidative stress markers and their measurement.
SELECTED PUBLICATIONS
Djordjevic, V., Kovac, M., Miljic, P., Murata, M., Takagi, A., Pruner, I., Francuski, D., Kojima, T., Radojkovic, D. A novel prothrombin mutation in two families with prominent thrombophilia - the first cases of antithrombin resistance in a Caucasian population (2013) Journal of Thrombosis and Haemostasis, 11 (10), pp. 1936-1939. http://www.ncbi.nlm.nih.gov/pubmed/23927452
Topic A, Francuski D, Markovic B, Stankovic M, Dobrivojevic S, Drca S, Radojkovic D. (2013) Gender-related reference intervals of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine determined by liquid chromatography-tandem mass spectrometry in Serbian population. Clin Biochem., 46(4-5):321-6. http://www.ncbi.nlm.nih.gov/pubmed/23261837
Narancic, T., Radivojevic, J., Jovanovic, P., Francuski, D., Bigovic, M., Maslak, V., Savic, V., Vasiljevic, B., O'Connor, K.E., Nikodinovic-Runic, J. (2013) Highly efficient Michael-type addition of acetaldehyde to β-nitrostyrenes by whole resting cells of Escherichia coli expressing 4-oxalocrotonate tautomerase Bioresource Technology, 142, pp. 462-46. http://www.ncbi.nlm.nih.gov/pubmed/23759430
Nikodinovic-Runic, J., Coulombel, L., Francuski, D., Sharma, N.D., Boyd, D.R., Ferrall, R.M.O., O'Connor, K.E. (2013) The oxidation of alkylaryl sulfides and benzo[b]thiophenes by Escherichia coli cells expressing wild-type and engineered styrene monooxygenase from Pseudomonas putida CA-3, Applied Microbiology and Biotechnology, 97 (11), pp. 4849-4858. http://www.ncbi.nlm.nih.gov/pubmed/22890778
Francuski B, Ivkovic B, Stojanovic I, Vladimirov S, Francuski D. 2-[2-(Trifluoromethyl)phenyl]-2H-1-benzopyran-4(3H)-one. Acta Crystallogr E. 2012; E68: 01522.
Jacimovic Z, Leovac V, Francuski D, Draskovic B, Bogdanovic G (2009) Crystal structure of dicholoro-(3,5-dimethyl-1H-pyrazole-1-carboxamidine-N,N')copper(II),Cu(C6H10N4)Cl2 Z Kristallogr NCS 224: 569-570.
Francuski D, Saenger W (2009) Crystal Structure of the Antitoxin–Toxin Protein Complex RelB–RelE from Methanococcus jannaschii J Mol Biol 393: 898-908. http://www.ncbi.nlm.nih.gov/pubmed/19712680
Alonso, J. C., Balsa, D., Cherny, I., Christensen, S. K., Espinosa, M., Francuski, D., et al. (2007). Bacterial Toxin-Antitoxin Systems as Targets for the Development of Novel Antibiotics. In R. A. Bonomo, & M. E. Tolmasky (Eds.), Enzyme-Mediated Resistance to Antibiotics: Mechanism, Dissemination, and Prospects for Inhibition (pp. 313-329). Washington, D.C.: ASM Press.