Alpha-1-antitrypsin (A1AT) deficiency is an autosomal recessive disorder that is most common genetic cause of liver disease in children and emphysema in adults.
The Laboratory for Molecular Biology is the only laboratory in our country performing molecular diagnostics of alpha-1-antitrypsin deficiency by detection of the two most common mutated alleles – Z and S. All patients with decreased plasma level of A1AT protein are indicated for testing, as well as those who develop pulmonary emphysema, chronic obstructive pulmonary disease (COPD) or liver disease at young age.

Since 2004. our laboratory has participated in the European Quality Control Program organized by DGKL, Reference Institute for Bioanalytics..

CONTACT:

Dragica Radojkovic, PhD

TEL: ++ 381 11 3976 658

FAX: ++ 381 11 3975 808

e-mail: qwert@eunet.rs